庫存單位: PKSH032360_50μg-ES

重組人 DNA 聚合酶 β/POLB 蛋白(His 標籤),50 μg

人類 DNA 聚合酶 β 在細胞中組成性表現。它填補了鹼基切除修復後形成的 DNA 間隙。修復聚合酶在鹼基切除修復中扮演關鍵角色。具有 5'-脫氧核糖-5-磷酸裂解酶 (dRP 裂解酶) 活性,可去除 5' 糖磷酸,也可充當 DNA 聚合酶,將一個核苷酸添加到出現的單核苷酸間隙的 3' 端。它以逐步分佈的方式進行「填補空白」的 DNA 合成,而不是像其他 DNA 聚合酶那樣以進行性的方式。此活性不會受到 DNA 聚合酶 β 抑制劑 Aphidicolin 的影響。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:不適用

Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後,立即存放在<-20°C的環境中。

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Calculated Molecular Weight:39.2 kDa

Observed Molecular Weight:39千道爾頓

Purity: 以還原 SDS-PAGE 測定,結果 > 95%。

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Storage:儲存溫度<-20°C,可穩定保存6個月。請盡量減少凍融循環。

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Calculated Molecular Weight:39.2 kDa

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Endotoxin: 經 LAL 方法測定,每 μg 蛋白質含量 < 1.0 EU。

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Research Areas:表觀遺傳學和核子訊號

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Bio-activity:未驗證活動

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Formulation:以 0.2 μm 過濾溶液的形式提供,其中含有 20mM Tris-HCl、100mM NaCl、1mM DTT、1mM EDTA、50% 甘油,pH 7.8。

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