Elabscience

庫存單位: PKSH033583_10μg-ES

重組人類 CD10/Neprilysin 蛋白（His 標籤），10 μg

腦啡肽/CD10（NEP）是一種在多種細胞的細胞表面表達的鋅金屬肽酶。其功能既是嗜熱菌蛋白酶樣特異性的內切肽酶，也是二肽基羧肽酶。已證明 NEP 參與哺乳動物腦中的腦啡肽的降解和循環心房利鈉肽的失活。 NEP 也被確定為常見的急性淋巴細胞白血病抗原 (CALLA)，並在某些疾病狀態下在淋巴細胞表面表達。這些觀察結果和其他觀察結果引起了人們對 NEP 作為止痛藥和抗高血壓藥物標靶的極大興趣。 NEP 也是腦內澱粉樣 β 肽 (Aβ) 的主要降解酶，這表明，由衰老引起的 NEP 活性下調可能透過促進 Aβ 積累而導致阿茲海默症的發展。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:不適用

Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後，立即存放在<-20°C的環境中。

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Calculated Molecular Weight:80.9 kDa

Observed Molecular Weight:94-100kDa

Purity: 以還原 SDS-PAGE 測定，結果 > 95%。

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Storage:儲存溫度<-20°C，可穩定保存6個月。請盡量減少凍融循環。

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Calculated Molecular Weight:80.9 kDa

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Endotoxin: 經 LAL 方法測定，每 μg 蛋白質含量 < 1.0 EU。

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Research Areas:癌症；免疫學；幹細胞

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Bio-activity:未驗證活動

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Formulation:以 0.2 μm PBS 過濾溶液（pH7.4）提供。

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