庫存單位: PKSH032067_50μg-ES

重組人 ANGPTL8/β-營養蛋白(Fc 標示),50 μg

此蛋白質特異性地促進胰臟β細胞增生和β細胞質量擴增,進而改善葡萄糖耐受性。它促進胰臟β細胞增殖,且不產生胰島素抗性。它還可以透過調節血清甘油三酯水平和可能促進 ANGPTL3 裂解來充當血脂調節劑。它與 ANGPTL3 相互作用。它主要在肝臟中表達,也在脂肪組織中表達。此蛋白質誘導胰臟β細胞增殖的能力在糖尿病治療中很有前景。 Betatrophin 治療可以透過增加糖尿病中產生胰島素的細胞數量來補充或取代胰島素注射。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:請參閱印刷手冊以取得詳細資訊。

Shipping:本產品以凍乾粉形式提供,並附冰袋運送。

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Calculated Molecular Weight:46.0 kDa

Observed Molecular Weight:54千道爾頓

Purity: 以還原 SDS-PAGE 測定,結果為 > 80%。

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Storage:一般來說,冷凍乾燥蛋白在-20至-80℃保存可穩定保存長達12個月。重建後的蛋白溶液可在4-8℃保存2-7天。重建樣品的等分試樣在 < -20℃ 穩定保存 3 個月。

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Calculated Molecular Weight:46.0 kDa

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Endotoxin: 經 LAL 方法測定,每 μg 蛋白質含量 < 1.0 EU。

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Research Areas:細胞生物學

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Bio-activity:未驗證活動

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Formulation:由 20mM 組胺酸-HCl、6% 海藻糖、4% 甘露醇、50mM NaCl、0.05% Tween 80、pH6.0 的 0.2 μm 過濾溶液冷凍乾燥。
通常在冷凍乾燥前會添加5%~8%的海藻糖、甘露醇和0.01%的吐溫80作為保護劑。
請參閱印刷手冊中的具體緩衝液資訊。

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