Elabscience

庫存單位: E-AB-81447_100μL-ES

重組Beclin 1單株抗體，100 μL

Beclin-1 (BECN1)，也稱為 ATG6 或 VPS30，在自噬作用中起著核心作用，自噬作用是一種程序性細胞存活過程，在細胞壓力期間會增加，而在細胞週期期間會消失。 Beclin-1可能在抗病毒宿主防禦中發揮作用。它可以預防辛德畢斯病毒神經毒性株的感染。 Beclin-1參與自噬的調控，在發育、腫瘤發生和神經退化性變中發揮重要作用。據報道，Beclin-1 表達的逐漸降低與肺鱗狀細胞癌和肺腺癌的原發性腫瘤生長有關。胱天蛋白酶介導的 Beclin 1 裂解促進了細胞凋亡和自噬之間的串擾。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:300微克/毫升

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Calculated Molecular Weight:52kDa

Observed Molecular Weight:52kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:52kDa

Dilution:廣譜 1:500-1:1000

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Application:世界銀行

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Research Areas:癌症;表觀遺傳學和核信號傳導；代謝;微生物學；訊號傳導

Species Reactivity:人類;老鼠;鼠

Reactivity:

Target Synonym:APG6;ATG 6;ATG6;ATG6 自噬相關 6 同源物;Bcl-2 相互作用蛋白 beclin;Beclin 1（捲曲螺旋肌球蛋白樣 BCL2 相互作用蛋白）；Beclin 1 自噬相關;Beclin-1;Beclin1;BECN 1;BeCL1;395;Beclin; 97;VPS 30;VPS30

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Buffer:50mM Tris-Glycine（pH 7.4）、0.15M NaCl、40% 甘油、0.01% 疊氮化鈉和 0.05% 保護蛋白

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Conjugation:未結合

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