Elabscience

庫存單位: E-AB-22126_200μL-ES

PPARD單株抗體，200 μL

此基因編碼過氧化物酶體增殖激活受體（PPAR）家族的一個成員。 PPAR 是核內激素受體，可結合過氧化物酶體增殖物並控制細胞產生的過氧化物酶體的大小和數量。 PPARs介導多種生物過程，可能參與多種慢性疾病的發展，包括糖尿病、肥胖、動脈粥狀硬化和癌症。這種蛋白質是 PPAR alpha 和 PPAR gamma 的配體誘導轉錄活性的強效抑制劑。它可能作為轉錄抑制和核受體訊號傳導的整合子發揮作用。發現該基因的表達在結直腸癌細胞中升高。結腸息肉腺瘤病 (APC) 是一種與 APC/β-catenin 訊號通路相關的腫瘤抑制蛋白，可以抑制這種升高的表達。

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1毫克/毫升

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:免疫組化 1:100-200；免疫螢光 1:100-200

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Application:免疫組化

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Research Areas:癌症；心血管；表觀遺傳學和核子訊號；代謝

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:FAAR；MGC3931；NR1C2；NUC1；NUCI；NUCII；核激素受體 1；核受體亞家族 1 組 C 成員 2；過氧化物酶體增殖激活受體 d​​elta；過氧化物酶體增殖激活受體 β (PPAR-β)；過氧化物酶體增殖激活受體 d​​elta；過氧化物酶體增殖激活受體 β (PPAR-β)；過氧化物酶體增殖；

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Buffer:含0.02％疊氮化鈉、0.5％保護蛋白和50％甘油的PBS，pH7.4

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Conjugation:未結合

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