Elabscience

庫存單位: E-AB-52741_60μL-ES

POLH 多株抗體，60 μL

此基因編碼 Y 家族專門的 DNA 聚合酶的成員。與其他 DNA 指導的聚合酶相比，它複製未受損的 DNA 的保真度較低。然而，它可以準確地複製受紫外線損傷的 DNA；當存在胸腺嘧啶二聚體時，這種聚合酶會將互補的核苷酸插入新合成的 DNA 中，從而繞過損傷並抑制紫外線引起的 DNA 損傷的致突變作用。這種聚合酶被認為參與了免疫球蛋白類別轉換重組過程中的高頻突變。該基因的突變會導致 XPV，即著色性乾皮症的變異。已發現該基因有幾種編碼不同異構體的轉錄變異。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Calculated Molecular Weight:78千道爾頓

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:78千道爾頓

Dilution:免疫印跡法 1:500-1:2000

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Application:免疫組化

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Research Areas:癌症；表觀遺傳學和核子訊號傳導

Species Reactivity:人;小鼠

Reactivity:

Target Synonym:DNA 聚合酶 eta；FLJ16395；FLJ21978；Polh；POLH；聚合酶 DNA 定向 eta；RAD30；RAD30 同源物 A；RAD30A；著色性乾皮症變異型蛋白；XP V；XPV

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Buffer:含 0.05% NaN3 和 40% 甘油的 PBS，pH7.4

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