庫存單位: AN002170P_25μg-ES

纖溶酶原激活劑/尿激酶單株抗體(捕獲),25 μg

此基因編碼一種絲氨酸蛋白酶,參與細胞外基質的降解以及可能的腫瘤細胞遷移和增殖。該基因的特定多態性可能與晚發性阿茲海默症以及纖維蛋白結合親和力降低有關。這種蛋白質透過特異性地裂解纖溶酶原中的 Arg-Val 鍵,將纖溶酶原轉化為纖溶酶。反過來,纖溶酶在 Lys-Ile 鍵處裂解該蛋白質,形成雙鏈衍生物,其中單個二硫鍵將氨基末端 A 鏈連接到具有催化活性的羧基末端 B 鏈。這種雙股衍生物也稱為HMW-uPA(高分子量uPA)。 HMW-uPA 可透過將鏈 A 裂解為短鏈 A (A1) 和氨基末端片段進一步加工為 LMW-uPA(低分子量 uPA)。 LMW-uPA 具有蛋白水解活性,但不能與 uPA 受體結合。已發現該基因有編碼不同異構體的剪接轉錄變異。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋,收到後,請立即在建議的溫度下存放。

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Concentration:1毫克/毫升

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Shelf Life:12個月

Storage:4°C 下儲存有效期限為 12 個月,-20°C 下儲存有效期限為長期儲存,避免凍融循環。

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Dilution:ELISA 捕捉 2-8 μg/mL

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Application:ELISA 捕獲

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Research Areas:癌症;心血管;代謝;神經科學

Species Reactivity:人類

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Target Synonym:UPA;u-PA;ATF;URK;UP-A;尿激酶;Abbokinase;

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Buffer:磷酸鹽緩衝溶液,pH 值為 7.2,含 0.05% proclin 300。

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Clonality:單複製

Conjugation:未結合

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