庫存單位: E-AB-20843_20μL-ES

磷酸化CHEK2(Thr68)多株抗體,20 μL

調節細胞週期檢查點和細胞凋亡以應對 DNA 損傷,特別是 DNA 雙股斷裂。透過對「Ser-216」進行磷酸化來抑制 CDC25C 磷酸酶,從而阻止進入有絲分裂。也可能在減數分裂中發揮作用。透過在「Thr-18」和「Ser-20」處的磷酸化來調節 TP53 腫瘤抑制因子。

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:中國

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Shipping:產品隨附冰袋,收到後,請立即在建議的溫度下存放。

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Concentration:1毫克/毫升

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Calculated Molecular Weight:61kDa

Observed Molecular Weight:61kDa

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Shelf Life:12個月

Storage:儲存於-20°C,有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:61kDa

Dilution:WB 1:500-1:2000;IHC 1:100-1:300;IF 1:50-1:200

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Features and Capabilities

Application:WB;IHC-p;IF

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Research Areas:癌症;表觀遺傳學和核子訊號傳導

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:CDS 1;Cds1;Cds1 同源物;檢查點激酶 2;檢查點樣蛋白 CHK2;CHEK 2;Chek2;Chk 2;​​CHK2 檢查點同源物 (S. pombe);CHK2 檢查點同源物;CHK2;hCds1;HuC45;激酶 Chk2;絲胺酸/蘇胺酸蛋白激酶 Chk2

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Buffer:含0.02%疊氮化鈉、0.5%保護蛋白和50%甘油的PBS,pH7.4

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Clonality:多克隆

Conjugation:未結合

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