Elabscience

庫存單位: E-AB-21540_120μL-ES

磷酸化 ATM (Ser1981) 多株抗體，120 μL

此基因編碼的蛋白質屬於 PI3/PI4-激酶家族。這種蛋白質是一種重要的細胞週期檢查點激酶，可以磷酸化；因此，它可以作為多種下游蛋白質的調節劑，包括腫瘤抑制蛋白 p53 和 BRCA1、檢查點激酶 CHK2、檢查點蛋白 RAD17 和 RAD9 以及 DNA 修復蛋白 NBS1。這種蛋白質和密切相關的激酶 ATR 被認為是細胞週期檢查點訊號路徑的主要控制器，而這些路徑是細胞對 DNA 損傷作出反應和基因組穩定性所必需的。此基因的突變與毛細血管擴張性共濟失調症（一種體染色體隱性遺傳疾病）有關。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1毫克/毫升

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Observed Molecular Weight:350kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:免疫印跡法 1:500-1:2000

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Application:WB;IHC-p

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Research Areas:癌症；表觀遺傳學和核子訊號傳導

Species Reactivity:人;小鼠

Reactivity:

Target Synonym:AT 突變；AT 突變同源物；AT 突變；AT1；ATA；毛細血管擴張性共濟失調突變；毛細血管擴張性共濟失調突變基因；毛細血管擴張性共濟失調突變同源物（人類）；毛細血管擴張性共濟失調突變同源物；ATC；ATD；ATDC；ATE；ATM；MATMMA8M4454574505745455554855542]（PTMGA47p；D4215755575555557p； 0232981；絲胺酸蛋白激酶 ATM；絲胺酸蛋白激酶 ATM；絲胺酸/蘇胺酸蛋白激酶 ATM；Tefu；TEL1；TEL1；端粒維持 1；同源物；TELO1；端粒融合蛋白

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Buffer:含0.02％疊氮化鈉、0.5％保護蛋白和50％甘油的PBS，pH7.4

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Clonality:多克隆

Conjugation:未結合

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