Elabscience

庫存單位: ELAB6082-M_1mL-ES

p63 單株抗體，1 毫升

p63基因是p53基因家族的成員之一，位於染色體3q27-28，編碼6個以上的主要異構體，分別具有轉錄激酶活性、死亡誘導活性（TAP63）和鉻失活活性。在胚胎時期，多種上皮細胞和器官都需要P63蛋白。 P63蛋白在肌上皮細胞中有表達，其效果較SMA好，但在肌纖維母細胞中不表達。近來研究表明，p63是前列腺基底細胞的標誌，在大多數前列腺腫瘤中並不表達，其意義與34bE12相似。由於p63是核陽性染色，而P504S是細胞質染色，因此將它們結合起來可以更容易判斷結果。

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