Elabscience

庫存單位: E-AB-22015_200μL-ES

P53單株抗體，200μL

在多種腫瘤類型中發揮腫瘤抑製作用；根據生理狀況和細胞類型誘導生長停滯或細胞凋亡。作為一種反式活化因子參與細胞週期調控，透過控制該過程所需的一組基因來負向調節細胞分裂。其中一種活化的基因是細胞週期依賴性激酶的抑制劑。細胞凋亡誘導似乎是透過刺激 BAX 和 FAS 抗原表現或抑制 Bcl-2 表現來介導的。與 Notch 訊號交叉有關。異構體 2 增強了異構體 1 從部分（但不是全部）TP53 誘導啟動子的轉錄活化活性。異構體 4 抑制轉錄活化活性並削弱異構體 1 介導的生長​​抑制。異構體 7 抑制異構體 1 介導的細胞凋亡。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1毫克/毫升

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Calculated Molecular Weight:44kDa

Observed Molecular Weight:53kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:44kDa

Dilution:WB 1:500-1:2000；IHC 1:100-1:300；IF 1:100-1:200

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Application:WB;IHC-p;IF

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Research Areas:癌症；細胞生物學；表觀遺傳學和核子訊號傳導

Species Reactivity:人類

Reactivity:

Target Synonym:抗原 NY-CO-13;BCC7;細胞腫瘤抗原 p53;FLJ92943;LFS1;突變腫瘤蛋白 53;p53;p53 腫瘤抑制因子;P53;磷蛋白 p53;Tp53;轉化相關蛋白 53;TRP53;腫瘤蛋白 53;腫瘤蛋白 p53；

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Buffer:含有 0.02% 疊氮化鈉和 50% 甘油的 PBS，pH 值為 7.4。

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Conjugation:未結合

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