Elabscience

庫存單位: E-AB-22162_60μL-ES

MAP2K2單株抗體，60 μL

此基因編碼的蛋白質是一種雙特異性蛋白激酶，屬於 MAP 激酶激酶家族。已知這種激酶在絲裂原生長因子訊號傳導中扮演關鍵角色。它磷酸化並因此活化 MAPK1/ERK2 和 MAPK2/ERK3。此激酶本身的活化依賴於 MAP 激酶激酶對 Ser/Thr 磷酸化。此基因突變會導致心面皮膚症候群 (CFC 症候群)，這種疾病的特徵是心臟缺陷、智力障礙以及與努南氏症候群相似的獨特面部特徵。此激酶的抑製或降解也被發現與耶爾森氏菌和炭疽病的發病機制有關。已鑑定出該基因的一個假基因，位於 7 號染色體上。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1毫克/毫升

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Observed Molecular Weight:45kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:WB 1:500-1:2000；IHC 1:100-1:300；IP 1:200-1:500

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Application:世界銀行

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Research Areas:癌症；訊號傳導

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:心面皮膚症候群；CFC 症候群；CFC4；雙特異性絲裂原活化蛋白激酶激酶 2；雙特異性絲裂原活化蛋白激酶激酶 2；ERK 活化劑激酶 2；FLJ26075；MAP 激酶激酶 2；map2k2；MAPK / ERK 激酶 2；MAPK/ERK 激酶激酶 2；map2k2；MAPK / ERK 激酶 2；MAPK/ERK 激酶激酶激酶 2；map2k2；MAPK / ERK 激酶 2；MAPK/ERK 激酶激酶激酶 2；map2k2；MAPK / ERK 激酶 2；MAPK/ERK 激酶激酶 2KKK 激酶激酶 222 激酶； ；絲裂原活化蛋白激酶激酶 2 p45；MKK 2；MKK2；MP2K2；OTTHUMP00000165826；OTTHUMP00000165827；PRKMK 2；PRKMK2

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Buffer:含0.02％疊氮化鈉、0.5％保護蛋白和50％甘油的PBS，pH7.4

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Conjugation:未結合

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