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庫存單位: E-AB-60646_200μL-ES
（KO 驗證）Caspase-3 多克隆抗體，200 μL
此基因編碼的蛋白質是半胱氨酸天門冬胺酸蛋白酶（caspase）家族的成員。胱天蛋白酶的連續活化在細胞凋亡的執行階段中起著核心作用。胱天蛋白酶以無活性的酶原形式存在，其在保守的天冬胺酸殘基處進行蛋白水解加工，產生兩個亞基（大亞基和小亞基），然後二聚化形成活性酶。這種蛋白質可裂解並活化胱天蛋白酶 6、7 和 9，而蛋白質本身則由胱天蛋白酶 8、9 和 10 加工。它是參與裂解澱粉樣蛋白-β 4A 前體蛋白的主要胱天蛋白酶，與阿茲海默症中的神經元死亡有關。該基因的選擇性剪接產生了編碼相同蛋白質的兩種轉錄變異。
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:中國
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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。
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Concentration:1毫克/毫升
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Calculated Molecular Weight:31kDa
Observed Molecular Weight:17kDa/35kDa
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Shelf Life:12個月
Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。
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Calculated Molecular Weight:31kDa
Dilution:免疫印跡法 1:500-1:2000
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Application:免疫組化
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Research Areas:癌症；細胞生物學；代謝；神經科學
Species Reactivity:人類;小鼠;大鼠
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Buffer:含 0.02% 疊氮化鈉、50% 甘油的 PBS，pH7.3。
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Clonality:多克隆
Conjugation:未結合
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