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庫存單位: AN006080L_100μL-ES
IL-3多株抗體，100 μL
IL3（白細胞介素 3）是一種蛋白質編碼基因。與 IL3 相關的疾病包括血液系統癌症和過敏性疾病。其相關途徑包括滑膜成纖維細胞凋亡途徑和 MIF 介導的糖皮質激素調節。細胞激素主要由活化的 T 淋巴細胞以及肥大細胞和成骨細胞分泌，控製造血祖細胞的產生和分化為譜系限制性細胞。也刺激成熟的嗜鹼性球、嗜酸性球和單核細胞進行功能活化。此外，在神經細胞增殖和存活中發揮重要作用。也參與骨穩態並透過阻止 NF-kappa-B 核轉位和活化來抑制破骨細胞分化。機制上，其透過由IL3RA亞基和訊號傳導亞基IL3RB組成的受體發揮其生物學作用。受體刺激導致JAK2激酶活性的快速激活，從而引發STAT5介導的轉錄程序。或者，透過活化 PI3K/AKT 和 ERK 介導的通路，有助於非造血系統中氧化壓力下的細胞存活。
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:中國
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Shipping:產品隨附冰袋，收到後請立即在建議的溫度下存放。
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Concentration:1毫克/毫升
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Shelf Life:12個月
Storage:儲存於-20°C，有效期限為 12 個月。避免凍融循環。避免長時間暴露於光線下。
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Dilution:免疫組化 1:500-1:1000
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Application:免疫組織化學
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Species Reactivity:人類
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Target Synonym:白血球介素；造血生長因子；白血球介素-3；肥大細胞生長因子；MCGF；MCSF；MULTI-CSF；多潛能集落刺激因子；P-細胞刺激因子；P-細胞刺激因子；Csfmu；Il-3；Il3
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Buffer:含0.02％疊氮化鈉、1％保護蛋白和50％甘油的PBS，pH7.4
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Clonality:多克隆
Conjugation:未結合
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