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庫存單位: E-AB-52192_120μL-ES
HSD11B1多株抗體，120 μL
此基因編碼的蛋白質是一種微粒體酶，可催化壓力荷爾蒙皮質醇轉化為無活性代謝物皮質松。此外，編碼的蛋白質可以催化逆反應，即皮質酮轉化為皮質醇。過多的皮質醇會導致中心肥胖，這種基因的特定變異與兒童肥胖和胰島素抗性有關。此基因和 H6PD（己糖-6-磷酸去氫酶（葡萄糖 1-脫氫酶））的突變是導致可的松還原酶缺乏的原因。可變剪接產生編碼相同蛋白質的多種轉錄變異。
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:中國
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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。
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Shelf Life:12個月
Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。
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Dilution:免疫組化 1:50-1:200
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Application:免疫組織化學
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Research Areas:癌症；代謝；訊號傳導
Species Reactivity:人類
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Target Synonym:11 beta HSD 1;11 beta HSD1;11 beta 羥基類固醇脫氫酶 1;11 DH;11-beta 羥基類固醇脫氫酶；1 型；11-beta-HSD1；11-beta-羥基類固醇脫氫酶 1；11-DH;beta-HSD1；11-beta-羥基類固醇去氫酶 1；11-DH; CORTRD2;DHI1;HDL;HSD 11;HSD11;HSD11B;HSD11B1;HSD11L;羥基類固醇 (11 beta) 脫氫酶;羥基類固醇 (11 beta) 脫氫酶 1;MGC13539;SDR26C1;SDR26C1; 26C；
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Buffer:含 0.05% NaN3 和 40% 甘油的 PBS，pH7.4
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