Elabscience

庫存單位: E-AB-53241_60μL-ES

HRAS多株抗體，60 μL

該基因屬於Ras致癌基因家族，該家族成員與哺乳動物肉瘤逆轉錄病毒的轉化基因有關。這些基因編碼的產物在訊號傳導途徑中發揮作用。這些蛋白質可以結合 GTP 和 GDP，並且具有內在的 GTPase 活性。這種蛋白質經歷連續的去棕櫚酰化和再棕櫚酰化循環，從而調節其在質膜和高爾基體之間的快速交換。此基因突變會導致科斯特洛綜合徵，這種疾病的特徵是產前生長加快，產後生長遲緩，易形成腫瘤，智力低下，皮膚和肌肉骨骼異常，面部外觀獨特以及心血管異常。此基因缺陷與多種癌症有關，包括膀胱癌、濾泡性甲狀腺癌和口腔鱗狀細胞癌。已鑑定出該基因的多個轉錄變體，它們編碼不同的異構體。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Calculated Molecular Weight:21千道爾頓

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:21千道爾頓

Dilution:免疫組化 1:500-1:2000

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Application:免疫組化

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Research Areas:癌症；細胞生物學；表觀遺傳學和核子訊號；訊號傳導

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:C BAS/HAS;c H ras;C HA RAS1;c has/bas p21 蛋白;c ras Ki 2 活化致癌基因;cH-ras;CTLO;GTP 和 GDP 結合勝肽 B;GTPase HRas;N 端加工;H Ras 1;H RASIH-K-Ras-1;Hat; HRAS;HRAS1;K ras;N ras;p19 H RasIDX 蛋白;p21ras;Ras 家族小 GTP 結合蛋白 H Ras;RASH;RASH1;轉化基因致癌基因 HAMSV;轉化蛋白 p21;v Ha ras Harvey 大鼠肉瘤病毒致癌基因同源物;VH Ras;vHa RAS

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Buffer:含 0.05% NaN3 和 40% 甘油的 PBS，pH7.4

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