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庫存單位: E-AB-19893_200μL-ES

GALR2 多株抗體，200 μL

GALR2（Galanin Receptor 2）是一種蛋白質編碼基因。其相關途徑包括勝肽配體結合受體和 GPCR 訊號傳導。與此基因相關的GO註釋包括G蛋白偶聯受體活性和甘丙肽受體活性。該基因的一個重要的旁系同源物是GALR3。 Galanin是存在於大腦、胃腸系統和下視丘腦下垂體軸的重要神經調節劑。它是一種 30 個胺基酸非 C 端醯胺化勝肽，能有效刺激生長激素分泌、抑制心臟迷走神經減慢心率、消除竇性心律不整、抑制餐後胃腸蠕動。甘丙肽的作用是透過與特定的膜受體相互作用來介導的，這些膜受體是 G 蛋白偶聯受體 7 跨膜家族的成員。 GALR2 與甘丙肽的 N 端殘基相互作用。 GALR2 的主要訊號傳導機制是透過磷脂酶 C/蛋白激酶 C 路徑（透過 Gq），而 GALR1 則透過 Gi 抑制腺苷酸環化酶來傳遞細胞內訊號。然而，事實已證明 GALR2 能有效地與 Gq 和 Gi 蛋白結合，同時活化 2 個獨立的訊號傳導路徑。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:0.66 毫克/毫升

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:免疫組化 1:30-1:150

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Application:免疫組織化學

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Research Areas:新陳代謝；神經科學

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:GAL2-R； GAL2R；甘丙肽受體2；甘丙肽受體2型；GALNR2；GALR-2；GALR2；GALR2；MGC125983；MGC125984

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Buffer:含 0.05% NaN3 和 40% 甘油的 PBS，pH7.4

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Conjugation:未結合

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