核酸內切酶 IV，10 KU

Brands:Beyotime

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Place of Origin:中國

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Shipping:藍冰/乾冰

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Component:內切酶 IV (10U/µl)、10X 內切酶 IV 緩衝液

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Purity:≥ 95%

Shelf Life:24個月

Storage:-20℃

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Test Principle:Beyotime Endonuclease IV 是一種從大腸桿菌表現和純化的重組核酸內切酶。這種酵素的作用是修復氧化性 DNA 損傷。它特異性辨識雙股 DNA（dsDNA）內的脫嘌呤/脫嘧啶（AP）位點，並切割 AP 位點 5' 端的磷酸二酯鍵，產生 3' 羥基和 5'-脫氧核糖磷酸（dRP）末端。內切酶 IV 具有 3'-二酯酶活性，可去除 3'-磷酸乙醇酸、3'-α，β-不飽和醛、磷酸乙醇醛或其他 3' 封閉基團。它還具有 3'-5' 外切酶活性，偏好具有 3' 凹端的 dsDNA。

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