Elabscience

庫存單位: E-AB-52777_60μL-ES

EIF3C 多株抗體，60 μL

真核翻譯起始因子 3 (eIF-3) 複合物的組成部分，是蛋白質合成起始的幾個步驟所必需的 (PubMed:17581632、PubMed:25849773、PubMed:27462815)。 eIF-3 複合物與 40S 核醣體結合並促進 eIF-1、eIF-1A、eIF-2：GTP：甲硫氨酰-tRNAi 和 eIF-5 的募集形成 43S 前起始複合物 (43S PIC)。 eIF-3 複合物刺激 mRNA 募集至 43S PIC 並掃描 mRNA 以進行 AUG 辨識。 eIF-3 複合物也是終止後核醣體複合物的拆卸和回收所必需的，隨後防止 40S 和 60S 核醣體亞基在啟動之前過早連接（PubMed：17581632）。 eIF-3 複合物特異性地靶向並啟動與細胞增殖（包括細胞週期、分化和凋亡）有關的一組 mRNA 的翻譯，並使用不同的 RNA 莖環結合模式來發揮翻譯激活或抑製作用（PubMed：25849773）。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:免疫組化 1:40-1:200

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Application:免疫組織化學

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Research Areas:表觀遺傳學和核子訊號

Species Reactivity:人類;小鼠;大鼠

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Target Synonym:細胞遷移誘導蛋白 17;eIF 3c;eIF3 p110;eIF3-p110;eIF3c;EIF3C;EIF3CL;EIF3S8;EIF3S8 蛋白;真核翻譯起始因子 3 亞基 8 (110kD); 核

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Buffer:含 0.05% NaN3 和 40% 甘油的 PBS，pH7.4

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