庫存單位: E-AB-11166_120μL-ES

DRG1多株抗體,120 μL

DRG1(發育調節 GTP 結合蛋白 1),也稱為 NEDD3(神經前體細胞表達的發育下調蛋白 3),是定位於細胞質的 367 個胺基酸蛋白質,屬於 GTP1/OBG 家族。 DRG1 在心臟、腎臟和骨骼肌中表達水平較高,而在腦、肝臟、胎盤、肺、結腸和脾臟中表達水平較低,它與 TAL1 和 TAL2 結合,被認為在細胞增殖和分化以及細胞凋亡中發揮作用,表明它在腫瘤形成和轉移中發揮作用。 DRG1 容易發生多泛素化和 SUMO 化,前者會誘導蛋白水解降解。編碼 DRG1 的基因位於人類 22 號染色體上,該染色體包含 500 多個基因,是人類第二小的染色體。位於 22 號染色體上的幾個基因的突變與 Phelan-McDermid 症候群、2 型神經纖維瘤病、自閉症和精神分裂症的發展有關。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋,收到後,請立即在建議的溫度下存放。

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Concentration:0.5毫克/毫升

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Calculated Molecular Weight:41kDa

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Shelf Life:12個月

Storage:儲存於-20°C,有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:41kDa

Dilution:免疫印跡法 1:500-1:2000

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Application:免疫組化

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Research Areas:癌症;細胞生物學;訊號傳導

Species Reactivity:人;小鼠

Reactivity:

Target Synonym:發育調節的 GTP 結合蛋白 1;發育調節的 GTP 結合蛋白 1;DKFZp434N1827;DRG 1;DRG-1;DRG1;DRG1;NEDD 3;NEDD-3;NEDD3;神經前體細胞表達發育下調蛋白 3;神經前體細胞表達下調蛋白 3

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS,PH7.4

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Clonality:多克隆

Conjugation:未結合

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