Elabscience

庫存單位: E-AB-70300_120μL-ES

CASP1多株抗體，120 μL

此基因編碼的蛋白質是半胱氨酸天門冬胺酸蛋白酶（caspase）家族的成員。胱天蛋白酶的連續活化在細胞凋亡的執行階段中起著核心作用。胱天蛋白酶以無活性的酶原形式存在，其在保守的天門冬胺酸殘基處進行蛋白水解加工，產生兩個大、小亞基，然後二聚化形成活性酶。該基因透過其蛋白水解裂解和激活白細胞介素-1的非活性前體的能力而被識別，白細胞介素-1是一種參與炎症、感染性休克和傷口癒合等過程的細胞因子。該基因已被證明能夠誘導細胞凋亡並可能在各個發育階段發揮作用。對小鼠類似基因的研究顯示其在亨丁頓舞蹈症的發病機制中發揮了作用。可變剪接產生編碼不同異構體的轉錄變異。

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1.2 毫克/毫升

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Calculated Molecular Weight:45kDa

Observed Molecular Weight:45-47kDa,30kDa,35kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:45kDa

Dilution:免疫印跡法 1:500-1:2000；免疫組織化學法 1:300-1:800

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Application:免疫組化

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Research Areas:癌症;細胞生物學；代謝

Species Reactivity:人類;老鼠;鼠

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Target Synonym:CASP-1；CASP1；CASP1；胱天蛋白酶 1；胱天蛋白酶-1 亞基 p10；ICE；IL-1 貝塔轉化酶；IL-1BC；IL1 貝塔轉化酶；IL1B 轉化酶；白介素 1 貝塔轉化酶；白介素 1B 轉化酶；IL1B 轉化酶；白介素 1 貝塔轉化酶；白介素 1B 轉化酶；白介白介素-1 15-5-p

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Buffer:含0.02％疊氮化鈉、1％保護蛋白和50％甘油的PBS，pH7.4

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Clonality:多克隆

Conjugation:未結合

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