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庫存單位: E-AB-18558_60μL-ES
C17orf67 多克隆抗體，60 μL
C17orf67（17 號染色體開放閱讀框 67）是一種由人類 17 號染色體基因編碼的 114 個胺基酸蛋白質。 17 號染色體佔人類基因組的 2.5% 以上，約有 8,100 萬個鹼基編碼超過 1,200 個基因。兩個關鍵的腫瘤抑制基因與 17 號染色體有關，即 p53 和 BRCA1。腫瘤抑制因子 p53 是維持細胞遺傳完整性所必需的，它透過 DNA 修復而不是細胞死亡來調節細胞命運。 p53 表現的功能障礙或喪失與惡性細胞生長和李-法美尼症候群有關。與 p53 一樣，BRCA1 直接參與 DNA 修復，具體來說，它被認為是早發性乳腺癌和卵巢癌、結腸癌、前列腺癌和輸卵管癌易感性的遺傳決定因素。 17 號染色體也與神經纖維瘤病有關，這種疾病的特徵是神經和表皮病變以及施萬細胞生長失調。亞歷山大氏症、Birt-Hogg-Dube 症候群和 Canavan 症也與 17 號染色體有關。
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:中國
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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。
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Concentration:0.7 毫克/毫升
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Shelf Life:12個月
Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。
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Dilution:免疫組化 1:40-1:200
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Application:免疫組織化學
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Research Areas:癌症；細胞生物學
Species Reactivity:人類
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Target Synonym:C17orf67；17號染色體開放閱讀框67； CQ067；未知蛋白 C17orf67
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Buffer:含 0.05% NaN3 和 40% 甘油的 PBS，pH7.4
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Clonality:多克隆
Conjugation:未結合
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