Elabscience

庫存單位: E-AB-15518_120μL-ES

AVEN多株抗體，120 μL

AVEN 是一種細胞死亡調節劑，是急性白血病中的重要訊號誘導劑。 AVEN 是一種高度保守的周邊膜蛋白，它透過幹擾 Apaf-1 的自我結合能力來保護細胞免受胱天蛋白酶的蛋白水解活化以及 Apaf-1 介導的細胞凋亡。 Bcl-2 和 Bad 也與 AVEN 相互作用以防止細胞凋亡。 AVEN 在卵巢、心臟、胸腺、脾臟、睪丸和結腸中高度表達，但也可在其他組織中檢測到。促紅血球生成素和甲基強的松龍可能在心臟組織中 AVEN 的表達中發揮重要作用，尤其是在腦外傷後。對於患有急性淋巴性白血病 (ALL) 的年輕患者，AVEN 表現可能是預後預測的有用工具。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:0.4 毫克/毫升

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Calculated Molecular Weight:39kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:39kDa

Dilution:免疫印跡法 1:500-1:2000；免疫組織化學法 1:25-1:100

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Application:免疫組化

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Research Areas:癌症；細胞生物學

Species Reactivity:人;小鼠

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Target Synonym:1700013A01Rik；1700056A21Rik；凋亡胱天蛋白酶活化抑制劑；AVEN；AVEN；細胞死亡調節劑Aven；mAven L；mAven S；MGC124011；OTTMUSP00000016129；PDCD12；程序性死亡12；

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4

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Conjugation:未結合

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