Elabscience

庫存單位: AN006020L_25μL-ES

AGER多株抗體，25 μL

AGER（高階糖化終產物特異性受體）是一種蛋白質編碼基因。與 AGER 相關的疾病包括糖尿病血管病變和高血糖。細胞表面模式辨識受體，可感知內源性壓力訊號，其配體庫廣泛，包括晚期糖化終產物、S100 蛋白、高遷移率族蛋白 B1 蛋白/HMGB1、澱粉樣蛋白 β/APP 寡聚體、核酸、磷脂質和醣胺聚醣。晚期糖化終產物是非酵素糖基化蛋白質，在老化過程中積聚在血管組織中，在糖尿病中積聚速度加快。這些配體在各種疾病（包括糖尿病、血管併發症、神經退化性疾病和癌症）的發病機制中積聚在發炎部位，而 RAGE 將它們的結合轉化為促發炎反應。當配體結合時，使用 TIRAP 和 MYD88 作為適配器來傳遞訊號，最終透過活化 NF-kappa-B 導致誘導或發炎細胞因子 IL6、IL8 和 TNFalpha。

$108.00 USD
$108.00 USD
2-4週
Hassle-Free Warranty
Safe & Secure Payment
Livetime Tech Support
  • Specification
  • Downloads
  • Reviews
$108.00
ADD TO CART
ADD TO CART

Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:中國

Warranty:

Safety Performance:

Protection Class:

Sterile Status:

Reconstitution:

Shipping:產品隨附冰袋，收到後請立即在建議的溫度下存放。

Battery:

Battery Service Life:

Component:

Technical Specifications

Capacity:

Concentration:1毫克/毫升

Dimension [D×W×H]:

Diameter:

Length:

Width:

High:

Volume:

Volume Range:

Speed:

Speed Range:

Max.Speed:

Max. RCF:

Temperature Range:

Operating Temperature Range:

Permissible Ambient Temperature :

Permissible Relative Humidity:

Input voltage:

Power Requirements:

Voltage/Frequency:

Sensitivity:

Specificity:

Precision:

Speed Accuracy:

Volume Accuracy:

Particle Size:

Pore Size:

Binding Capacity:

Calculated Molecular Weight:42千道爾頓

Observed Molecular Weight:43千道爾頓

Purity:

Shelf Life:12個月

Storage:儲存於-20°C，有效期限為 12 個月。避免凍融循環。避免長時間暴露於光線下。

Random Error:

Acceleration/Braking time:

Aspiration Speed:

Calculated Molecular Weight:42千道爾頓

Dilution:免疫印跡 1:5000-1:10000；免疫組織化學 1:100-1:200

Driving Motor DC motor:

Em:

Ex:

Endotoxin:

Flow rate [liquid]:

Features and Capabilities

Application:免疫組化

Detection Target:

Detection Type:

Detection Range:

Research Areas:神經科學；心血管

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:MGC；SCARJ；AGER；RAGE；SCARJ1；晚期糖化終產物特異性受體；晚期糖化終產物特異性受體；MGC2235；晚期糖化終產物受體；晚期糖化終產物受體

Test Principle:

Quantitative/Qualitative :

Result Type:

Materials :

Assay Time:

Autoclave component:

Available Rotor Adapters:

Binding Capacity:

Bio-activity:

Bottom Shape:

Bottom Type:

Buffer:含0.02％疊氮化鈉、1％保護蛋白和50％甘油的PBS，pH7.4

Cap Color:

Clonality:多克隆

Conjugation:未結合

Coupled Ligand:

Cover Type:

Detection Instrument :

Dispensing Speed:

Display:

Form:

Formulation:

Graduation:

Growth Area:

Download File