庫存單位: AN000200P_100μg-ES

脂聯素/Acrp30多克隆抗體(捕獲/檢測),100 μg

脂聯素,又稱 30 kDa 脂肪細胞補體相關蛋白 (Acrp30)、adipoQ、脂肪最豐富基因轉錄物 1 (apM1) 和 28 kDa 明膠結合蛋白 (GBP28),是一種脂肪細胞特異性分泌蛋白,在葡萄糖和脂質穩態中具有潛在作用。循環中脂聯素濃度較高,約佔血漿總蛋白的0.01%。脂聯素含有模組化結構,包括 N 端膠原蛋白結構域和隨後的 C 端球狀結構域,其序列和結構與補體因子 C1q 有顯著的相似性。儘管它們之間的序列同一性很小,但相似的三維結構和某些保守的氨基酸殘基表明脂聯素的 C1q 樣結構域與 TNF 超家族成員之間存在進化聯繫。脂聯素組裝成不同的複合物,包括三聚體(低分子量)、六聚體(中等分子量)和更高級的寡聚結構(高分子量),這些複合物可能影響生物活性。脂聯素在脂肪細胞分化過程中被誘導,其分泌受到胰島素的刺激。兩種脂聯素受體,分別稱為 AdipoR1 和 AdipoR2,已被克隆。儘管功能上與 G 蛋白偶聯受體不同,這些基因編碼的預測蛋白質含有 7 個跨膜結構域。 AdipoR1在骨骼肌中高度表達,而AdipoR2主要存在於肝臟組織中。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋,收到後,請立即在建議的溫度下存放。

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Concentration:1毫克/毫升

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Shelf Life:12個月

Storage:4°C 下儲存有效期限為 12 個月,-20°C 下儲存有效期限為長期儲存,避免凍融循環。

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Dilution:ELISA 捕捉 2-8 μg/mL;ELISA 檢測 0.1-0.4 μg/mL

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Application:ELISA 擷取/檢測儀

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Target Synonym:Acrp30;Adipoq;Adid;30 kDa 脂肪細胞補體相關蛋白;脂聯素 d;脂聯素;含 C1Q 和膠原蛋白結構域

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Buffer:磷酸鹽緩衝溶液,pH 值為 7.2,含 0.05% proclin 300。

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Clonality:多克隆

Conjugation:未結合

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