Elabscience

庫存單位: D-AB-10207L_100μL-ES

JNK2多株抗體，100 μL

此基因編碼的蛋白質是 MAP 激酶家族的成員。 MAP激酶作為多種生化訊號的整合點，參與增殖、分化、轉錄調控和發育等多種細胞過程。該激酶以特定的轉錄因子為目標，從而介導響應各種細胞刺激的即時早期基因表現。它與 MAPK8 關係最為密切，兩者都參與紫外線誘導的細胞凋亡，被認為與細胞色素 c 介導的細胞死亡途徑有關。該基因和 MAPK8 也被稱為 c-Jun N-端激酶。這種激酶阻斷腫瘤抑制因子 p53 的泛素化，從而增加非壓力細胞中 p53 的穩定性。對該基因在小鼠中的對應物的研究表明其在 T 細胞分化中發揮關鍵作用。已報告了幾種編碼不同亞型的剪接轉錄變異體。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1毫克/毫升

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Calculated Molecular Weight:48kDa

Observed Molecular Weight:46kDa,54kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:48kDa

Dilution:廣漢 1:5000-1:10000

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Application:世界銀行

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Research Areas:訊號傳導；細胞生物學；癌症；免疫學；代謝

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:c Jun 激酶 2；C Jun N 端激酶 2；c-Jun N-末端激酶 2；JNK 55；JNK-55；JNK2 alpha；JNK2；JNK2 beta；JNK2A；JNK2alpha；JNK2B；JNK2BETA；Jun 激酶MAP MAP 激酶 990K 909； P54a；p54aSAPK；PRKM9；蛋白激酶；絲裂原活化；9；SAPK alpha；SAPK；SAPK1a；壓力活化蛋白激酶 1a；壓力活化蛋白激酶 JNK2

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Buffer:含0.02％疊氮化鈉、1％保護蛋白和50％甘油的PBS，pH7.4

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Clonality:多克隆

Conjugation:未結合

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