Elabscience

庫存單位: E-AB-10383_120μL-ES

DFFA多株抗體，120 μL

細胞凋亡是哺乳動物發育過程中去除有毒和/或無用細胞的細胞死亡過程。細胞凋亡過程伴隨著細胞和細胞核的收縮和碎裂以及染色體 DNA 降解為核小體單位。 DNA 碎片因子 (DFF) 是 40 kD (DFFB) 和 45 kD (DFFA) 亞基的異二聚體蛋白。 DFFA 是 caspase-3 的底物，可在細胞凋亡過程中觸發 DNA 碎片化。當 DFFA 被 caspase-3 切割時，DFF 就會被活化。 DFFA 的裂解片段與 DFF 的活性成分 DFFB 分離。研究發現，DFFB 在細胞凋亡過程中會引發 DNA 碎片和染色質凝聚。已發現該基因有兩種編碼不同異構體的剪接轉錄變異。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:0.7 毫克/毫升

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:免疫組化 1:30-1:150

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Application:免疫組織化學

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Research Areas:癌症；細胞生物學；表觀遺傳學和核信號；代謝

Species Reactivity:人類

Reactivity:

Target Synonym:A330085O09Rik；胱天蛋白酶活化脫氧核糖核酸酶抑制劑簡寫；DFF 1；DFF 45；DFF α；DFF-45；DFF1；DFF35；DFF45；DFFA；Dffa DNA 碎片因子；α亞基；DFFA；DNA 碎片因子 45 k 亞碎片因子； DNA 碎片因子；45kDa；α多肽 (DFFA)；轉錄變異 1；DNA 碎片因子；45kDa；α多肽；DNA 碎片因子；α亞基；DNA 化因子 45 kDa 亞基；H13；ICAD；ICAD L；ICAD S；CAD抑制劑；胱天蛋白酶活化抑制劑DNase；MGC143066；OTTHUMP00000001903；OTTHUMP00000001904；RP23 121D17.3

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4

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Clonality:多克隆

Conjugation:未結合

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