Elabscience

庫存單位: D-AB-10383L_25μL-ES

CDNF多株抗體，25 μL

腦多巴胺神經營養因子 (CDNF)，也稱為 ARMETL1 (ARMET 樣蛋白 1)，是一種具有 8 個保守半胱氨酸殘基的分泌蛋白，預示著獨特的蛋白質折疊並定義了一個新的、進化保守的蛋白質家族。 CDNF 是一種新型神經營養因子，對多巴胺能神經元具有強大的營養活性，可與神經膠質細胞源性神經營養因子 (GDNF) 相媲美。 CDNF/ARMETL1是一種進化上保守的蛋白，其能夠保護和恢復帕金森氏症大鼠模型中多巴胺能神經元的功能，提示CDNF可能對帕金森氏症的治療有益。 CDNF廣泛表達於大腦皮質、海馬、黑質、紋狀體和小腦等多個腦區的神經元。人類 CDNF 被糖基化並從瞬時轉染的細胞分泌出來。 CDNF 促進多巴胺特異性神經元的存活、生長和功能，並在經歷可卡因誘導的神經可塑性的大腦區域中表達。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1毫克/毫升

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Calculated Molecular Weight:21kDa

Observed Molecular Weight:17kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:21kDa

Dilution:廣譜 1:500-1:1000

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Application:世界銀行

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Research Areas:神經科學

Species Reactivity:鼠

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Target Synonym:腦多巴胺神經營養因子；ARMET 樣蛋白 1；保守多巴胺神經營養因子；CDNF；ARMETL1

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Buffer:含0.02％疊氮化鈉、1％保護蛋白和50％甘油的PBS，pH7.4

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Conjugation:未結合

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