Elabscience

庫存單位: E-AB-81532_100μL-ES

重組ASK1單株抗體，100μL

絲裂原活化蛋白激酶 (MAPK) 訊號級聯包括 MAPK 或細胞外訊號調節激酶 (ERK)、MAPK 激酶 (MKK 或 MEK) 和 MAPK 激酶激酶 (MAPKKK 或 MEKK)。 MAPKK激酶/MEKK磷酸化並活化其下游蛋白激酶MAPK激酶/MEK，進而活化MAPK。這些訊號級聯的激酶高度保守，並且在酵母、果蠅和哺乳動物細胞中存在同源物。 MAPKKK5 含有 1,374 個胺基酸，包含全部 11 個激酶亞結構域。北方印跡分析表明，MAPKKK5轉錄本在人類心臟和胰腺中大量表達。 MAPKKK5 蛋白在體外磷酸化並激活 MKK4（別名 SERK1、MAPKK4），並在 COS 和 293 細胞中的瞬時表達期間激活 c-Jun N-末端激酶（JNK）/應激活化蛋白激酶（SAPK）； MAPKKK5 不激活 MAPK/ERK。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:300微克/毫升

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Calculated Molecular Weight:155kDa

Observed Molecular Weight:155kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:155kDa

Dilution:廣譜 1:500-1:1000

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Application:世界銀行

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Research Areas:癌症;細胞生物學；心血管

Species Reactivity:人類

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Target Synonym:凋亡訊號調節激酶 1;凋亡訊號調節激酶 1;ASK 1;ASK-1;ASK1;M3K5;M3K5;MAP/ERK 激酶激酶 5;MAP3K5;MAPK/ERK 激酶激酶 5;MAPKKK5;MEK 激酶 5;MEKK 5;MEKK5;

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Buffer:50mM Tris-Glycine（pH 7.4）、0.15M NaCl、40% 甘油、0.01% 疊氮化鈉和 0.05% 保護蛋白

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Clonality:兔單克隆

Conjugation:未結合

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