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庫存單位: E-AB-52169_200μL-ES
NR0B2多株抗體，200 μL
此基因編碼的蛋白質是一種不尋常的孤兒受體，含有假定的配體結合域，但缺乏常規的 DNA 結合域。此基因產物是核內激素受體家族的成員，該家族是一組由小疏水性荷爾蒙調控的轉錄因子，其中一部分沒有已知的配體，稱為孤兒核受體。該蛋白質已被證明能與類視黃酸和甲狀腺激素受體相互作用，抑制其配體依賴性轉錄活化。此外，已證實其與雌激素受體相互作用，導致功能抑制。研究表明，該蛋白質透過兩個獨立的步驟抑制核激素受體介導的轉錄活化：與輔激活因子的競爭以及其轉錄抑制功能的直接影響。
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:中國
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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。
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Shelf Life:12個月
Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。
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Dilution:免疫組化 1:30-1:150
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Application:免疫組織化學
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Research Areas:癌症；表觀遺傳學和核子訊號；代謝；訊號傳導
Species Reactivity:人類;小鼠;大鼠
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Target Synonym:NR0B2；NR0B2；Nr0b2a；核受體亞家族0 B組成員2；核受體亞家族0；B組；成員 2a；孤兒核受體 SHP；SHP；SHP-1；Shp1；小異二聚體伴侶
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Buffer:含 0.05% NaN3 和 40% 甘油的 PBS，pH7.4
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