Elabscience

庫存單位: E-AB-15735_200μL-ES

JNK2多株抗體，200 μL

透過磷酸化多種轉錄因子（主要是 AP-1 的成分，例如 c-Jun 和 ATF2）來回應環境壓力和促發炎細胞因子的激活，從而調節 AP-1 轉錄活性。在 T 細胞中，JNK1 和 JNK2 是 T 輔助細胞向 Th1 細胞極化分化所必需的。 JNK2 同工型表現出不同的結合模式：alpha-1 和 alpha-2 優先與 c-Jun 結合，而 beta-1 和 beta-2 與 ATF2 結合。然而，結合和磷酸化之間沒有相關性，所有同工型都以大致相同的效率實現磷酸化。 JUNB 不是 JNK2 alpha-2 的底物，且 JUND 與其結合力較弱。

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:0.4 毫克/毫升

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Calculated Molecular Weight:48kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:48kDa

Dilution:免疫印跡法 1:500-1:2000；免疫組織化學法 1:25-1:100

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Application:免疫組化

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Research Areas:癌症；細胞生物學；代謝；免疫學；訊號傳導

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:c Jun 激酶 2；C Jun N 端激酶 2；c-Jun N 端激酶 2；JNK 55；JNK-55；JNK2 alpha；JNK2；JNK2 beta；JNK2A；JNK2alpha；JNK2B；JNK2BETA；Jun 激酶；JNK2A；JNK2alpha；JNK2B；JNK2BETA；Jun 激酶；MAP 激酶 995K 4949； a；p54aSAPK；PRKM9；蛋白激酶；絲裂原活化；9；SAPK alpha；SAPK；SAPK1a；壓力活化蛋白激酶 1a；壓力活化蛋白激酶 JNK2

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4

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Clonality:多克隆

Conjugation:未結合

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