Elabscience

庫存單位: E-AB-16381_120μL-ES

DEAF1多株抗體，120 μL

抑制素，也稱為 DEAF1（變形表皮自調節因子 1）、SPN、NUDR（核 DEAF-1 相關轉錄調節因子）或 ZMYND5（鋅指 MYND 結構域蛋白 5），是胚胎髮育所需的轉錄因子。 Suppressin 含有一個 SAND 結構域和一個 C 端 MYND 型鋅指。它與 LMO4 和 CLIM-2 相互作用，表明它在介導細胞命運和胚胎模式形成中發揮作用。抑制素在多種組織中表現並定位於細胞核中。由於可變剪接，存在幾種亞型，並且根據亞型的不同，Suppressin 會在某些細胞類型中分泌。分泌的抑制素可以起到抑制細胞增生的作用，將細胞停滯在G0或G1期。編碼抑制素的基因突變可能導致生長優勢，進而引發腫瘤的發展和進展。這顯示抑制素是癌症治療的潛在目標。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1.4 毫克/毫升

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:免疫組化 1:50-1:200

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Application:免疫組織化學

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Research Areas:細胞生物學；表觀遺傳學和核子訊號傳導

Species Reactivity:人類

Reactivity:

Target Synonym:Deaf1;DEAF1轉錄因子;DEAF1;變形表皮自調節因子1同源物;核DEA1相關轉錄調節因子;核DEAF-1相關轉錄調節因子;NUDR;SPN;抑制素;含鋅指MYND結構域蛋白5;含鋅指MYND結構域蛋白5;ZMYND5

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4

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Conjugation:未結合

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