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庫存單位: E-AB-70168_120μL-ES
β澱粉樣蛋白多株抗體，120 μL
Aβ 由 APP 在蛋白酶（稱為 α-、β- 和 γ-分泌酶）的水解下產生。 α-分泌酶裂解會阻止 Aβ 的形成，而 β-和 γ-裂解會產生具有澱粉樣變性特徵的 APP 成分。澱粉樣β蛋白A4前驅蛋白(APP)由位於人類21q染色體上的APP基因編碼,是一種細胞表面受體,在神經元表面發揮與神經突生長、神經元黏附和軸突發生相關的生理功能。 APP在胎兒所有組織中均有表達,在腦、腎、心臟和脾臟中表達明顯,在肝臟中表達較弱。 APP 缺陷是導致第 1 型阿茲海默症 (AD1) 的病因。
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:中國
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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。
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Concentration:308微克/毫升
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Shelf Life:12個月
Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。
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Dilution:免疫組化 1:200-1:800
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Features and Capabilities
Application:免疫組織化學
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Research Areas:癌症;神經科學
Species Reactivity:老鼠;鼠
Reactivity:
Target Synonym:A4 澱粉樣蛋白；A4；AAA；ABETA；ABPP；AD1；AICD-50；AICD-57；AICD-59；AID(50)；AID(57)；AID(59)；阿茲海默症澱粉樣蛋白；澱粉樣蛋白 β (A4) 前蛋白樣蛋白 β；澱粉胞樣蛋白蛋白結構；結構域 59；澱粉樣蛋白前驅蛋白；APP；APPI；β 澱粉樣勝肽；β-澱粉樣蛋白前驅蛋白；β-APP40；β-APP42；C31；腦血管澱粉樣勝肽；CTFgamma；CVAP；Gamma-CTF(50)；Gamma-CTF(57)； II；PN-II；PN2；PreA4；蛋白酶連接蛋白II；蛋白酶連接蛋白-II；S-APP-alpha；S-APP-beta
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Buffer:含0.02％疊氮化鈉、1％保護蛋白和50％甘油的PBS，pH7.4
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Clonality:多克隆
Conjugation:未結合
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