Elabscience

庫存單位: E-AB-70146_120μL-ES

ATF1多株抗體，120 μL

此基因編碼一種活化轉錄因子，屬於 ATF 亞家族和 bZIP（鹼性區亮氨酸拉鍊）家族。它透過調節與生長、存活和其他細胞活動相關的下游目標基因的表達來影響細胞生理過程。此蛋白質在其激酶誘導域的絲氨酸 63 位點被絲氨酸/蘇氨酸激酶、cAMP 依賴性蛋白激酶 A、鈣調蛋白依賴性蛋白激酶 I/II、絲裂原和應激活化蛋白激酶以及細胞週期蛋白依賴性激酶 3 (cdk-3) 磷酸化。它的磷酸化增強了其轉錄活化和轉錄活性，增強了細胞轉化。此基因與16號染色體上的FUS或22號染色體上的EWSR1透過易位融合，在血管瘤樣纖維組織細胞瘤和透明細胞肉瘤產生嵌合蛋白。該基因在6號染色體上有一個假基因。

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:0.59 毫克/毫升

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Calculated Molecular Weight:29kDa

Observed Molecular Weight:29kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:29kDa

Dilution:廣譜 1:500-1:1000

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Application:世界銀行

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Research Areas:癌症;表觀遺傳學和核子訊號

Species Reactivity:人類;老鼠;鼠

Reactivity:

Target Synonym:活化轉錄因子 1;ATF 1;atf1;ATF1 EWS 融合基因;ATF1 FUS 融合基因;ATF1;cAMP 依賴性轉錄因子 1;cAMP 依賴性轉錄因子 ATF-1;環 AMP 依賴性轉錄因子 ATF 1;環 AMP 依賴性轉錄因子 ATF11 AMPTFTFS ATF 4TF;蛋白質活化轉錄因子 1 融合蛋白;TREB 36;TREB36;TREB36 蛋白

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Buffer:含0.02％疊氮化鈉、1％保護蛋白和50％甘油的PBS，pH7.4

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Conjugation:未結合

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