Elabscience

庫存單位: E-AB-30491_120μL-ES

AMPK alpha1/2多株抗體，120 μL

AMPK（5'-AMP活化蛋白激酶）是一種異三聚體複合物，由催化α亞基和調節β和γ亞基組成。它透過關閉消耗 ATP 的生物合成途徑來保護細胞免受導致 ATP 耗盡的壓力。 AMPK 透過高 AMP 和低 ATP 激活，其機制包括變構調節、上游蛋白激酶（稱為 AMPK 激酶）促進磷酸化、抑制去磷酸化。活化的 AMPK 可以磷酸化和調節體內羥甲基戊二酰輔酶 A 還原酶和乙醯輔酶 A 羧化酶，它們分別是固醇合成和脂肪酸合成的關鍵調節酶。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1毫克/毫升

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Calculated Molecular Weight:62kDa

Observed Molecular Weight:63kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:62kDa

Dilution:免疫印跡法 1:500-1:2000；免疫組織化學法 1:100-1:300

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Application:WB;IHC-p

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Research Areas:癌症；心血管；代謝；神經科學；訊號傳導

Species Reactivity:人;小鼠;大鼠;猴

Reactivity:

Target Synonym:PRKAA1;AMPK1;5'-AMP 活化蛋白激酶催化亞基 α-1;AMPK 亞基 α-1;乙醯輔酶 A 羧化酶激酶;ACACA 激酶;羥甲基戊二酰輔酶 A 還原酶激酶;HMGCR 激酶;Tau 蛋白激酶 PRKAA1;PRKAA2;AMPK;

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Buffer:含0.02％疊氮化鈉、0.5％保護蛋白和50％甘油的PBS，pH7.4

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Clonality:多克隆

Conjugation:未結合

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