Elabscience

庫存單位: E-AB-13198_60μL-ES

DIO2 多株抗體，60 μL

此基因編碼的蛋白質屬於碘甲狀腺原氨酸脫碘酶家族。它透過將外環脫碘（ORD）將激素原甲狀腺素 (T4) 轉化為生物活性的 3,3',5-三碘甲狀腺原氨酸 (T3) 來活化甲狀腺激素。它在甲狀腺中高度表達，可能對格雷夫茲病和甲狀腺腺瘤患者的甲狀腺 T3 生成相對增加有顯著貢獻。該蛋白質含有由 UGA 密碼子編碼的硒半胱氨酸 (Sec) 殘基，通常表示翻譯終止。含 Sec 基因的 3' UTR 具有共同的莖環結構，即 sec 插入序列 (SECIS)，這是將 UGA 識別為 Sec 密碼子而不是終止訊號所必需的。可變剪接產生編碼不同亞型的多個轉錄變異。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:0.9 毫克/毫升

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:免疫組化 1:25-1:100

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Application:免疫組織化學

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Research Areas:癌症；代謝；神經科學；訊號傳導

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:5DII;D2;脫碘酶;碘甲狀腺原氨酸;II 型;DIO2;DIOII;EC 1.97.1.10;IOD2;ITDI2;SelY;甲狀腺素脫碘酶;II 型;TXDI2;2 型 DI;2 型碘甲狀腺原氨酸脫碘酶;II 型 5' 脫碘酶脫碘酶。

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4

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Conjugation:未結合

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