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庫存單位: E-AB-13841_60μL-ES
COX10多株抗體，60 μL
細胞色素c氧化酶（COX）是粒線體呼吸鏈的末端成分，可催化還原型細胞色素c轉移到氧氣的電子。此成分為異源複合體，由粒線體基因編碼的3個催化亞基和核基因編碼的多個結構亞基組成。粒線體編碼的亞基在電子轉移中起作用，而核編碼的亞基可能在複合物的調節和組裝中起作用。此核基因編碼血紅素A：法呢基轉移酶，它不是結構亞基，但卻是功能性COX表達所必需的，並在COX的血紅素A輔基的成熟過程中發揮作用。預測該蛋白質含有 7-9 個位於粒線體內膜的跨膜結構域。基因突變導致賴氨酸被天冬酰胺 (N204K) 取代，這被認為是導致細胞色素 c 氧化酶缺乏的原因。此外，在患有 CMT1A（Charcot-Marie-Tooth 1A 型）重複和 HNPP（容易發生壓力性麻痺的遺傳性神經病變）缺失的患者中，該基因會被破壞。
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:中國
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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。
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Concentration:0.4 毫克/毫升
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Shelf Life:12個月
Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。
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Dilution:免疫組化 1:50-1:200
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Application:免疫組織化學
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Research Areas:癌症；代謝；訊號傳導
Species Reactivity:人類
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Target Synonym:2410004F01Rik；AU042636；COX10；COX10；細胞色素 c 氧化酶組裝蛋白；細胞色素 c 氧化酶亞基 X；血紅素 A 法呢基轉移酶；血紅素 O 合成酶；OTTMUSP00000006085； 8H18.1
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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4
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Clonality:多克隆
Conjugation:未結合
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