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庫存單位: E-AB-13099_60μL-ES
CBL 多株抗體，60 μL
此基因為原癌基因，編碼環指 E3 泛素連接酶。編碼的蛋白質是蛋白酶體降解底物所需的酵素之一。此蛋白質介導泛素從泛素結合酶 (E2) 轉移到特定底物。該蛋白質還含有 N 端磷酸酪胺酸結合域，使其能夠與多種酪胺酸磷酸化底物相互作用並將其作為蛋白酶體降解的目標。因此，它可作為許多訊號傳導路徑的負調節劑。研究發現，該基因在包括急性髓細胞白血病在內的許多癌症中發生突變或易位。此基因突變也是努南氏症候群樣疾病的原因
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:中國
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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。
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Concentration:0.4 毫克/毫升
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Calculated Molecular Weight:100kDa
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Shelf Life:12個月
Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。
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Calculated Molecular Weight:100kDa
Dilution:寬螢幕 1:500-1:2000
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Features and Capabilities
Application:世界銀行
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Research Areas:癌症；細胞生物學；表觀遺傳學和核子訊號；訊號傳導
Species Reactivity:人;小鼠
Reactivity:
Target Synonym:4732447J05Rik;C CBL;Cas Br M (鼠) 嗜性逆轉錄病毒轉化序列;Casitas B 譜系淋巴瘤原癌基因;Casitas B 譜系淋巴瘤原癌基因;CBL 2;cbl;CBL;CBL2;E3 泛素蛋白連接酶 CBL;CBL 2;cbl;CBL;CBL2;E3 泛素蛋白連結酶 CBL;CBL 2;cbl;CBL;CBL2;E3 泛素蛋白連結酶 CBL; 6;環指蛋白 55;RNF55;訊號傳導蛋白 CBL
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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4
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Clonality:多克隆
Conjugation:未結合
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