Elabscience

庫存單位: E-AB-13421_20μL-ES

CAB39多克隆抗體，20 μL

Peutz-Jeghers 症候群 (PJS) 是一種罕見的遺傳性疾病，其特徵是唇部黑色素細胞斑疹、胃腸道錯構瘤性息肉以及多種癌症的風險增加。絲胺酸/蘇胺酸激酶 LKB1（也稱為 STK11）已被確定為 PJS 中發生突變的基因。當由 STE20 相關適配器-α (STRAD α) 假激酶和鈣結合蛋白 39 (MO25 α) 組成的調節複合物結合時，LKB1 活性會增加。 STRAD 和 MO25 透過啟動 LKB1 從細胞核到細胞質的易位來決定 LKB1 的亞細胞定位，從而調節 LKB1 的腫瘤抑制活性。 LKB1/STRAD/MO25 複合物可作為 AMP 活化蛋白激酶激酶 (AMPKK)。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1.7 毫克/毫升

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Calculated Molecular Weight:40kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:40kDa

Dilution:免疫印跡法 1:500-1:2000

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Application:免疫組化

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Research Areas:癌症；代謝；訊號傳導

Species Reactivity:人;小鼠

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Target Synonym:Cab39；CAB39；鈣結合蛋白 39；鈣結合蛋白 39；CGI 66；CGI-66；CGI66；MO25 α；MO25；小鼠蛋白 25 α；蛋白質 Mo25

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4

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Clonality:多克隆

Conjugation:未結合

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