庫存單位: E-AB-12372_120μL-ES

DUT 多克隆抗體,120 μL

此基因編碼核苷酸代謝所必需的酵素。編碼的蛋白質形成一種普遍存在的同型四聚體酶,可將 dUTP 水解為 dUMP 和焦磷酸。此反應對細胞有兩個作用:為 DNA 複製所需的胸腺嘧啶核苷酸的合成提供前體 (dUMP),並限制細胞內的 dUTP 池。 dUTP 水平升高導致尿嘧啶更多地摻入 DNA,從而誘導尿嘧啶糖基化酶介導的廣泛切除修復。此修復過程會導致 dUTP 的去除和重新整合,但卻適得其反,導致 DNA 碎片化和細胞死亡。此基因的選擇性剪接會產生定位於粒線體或細胞核的不同亞型。相關的假基因位於19號染色體上。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋,收到後,請立即在建議的溫度下存放。

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Concentration:0.2毫克/毫升

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Calculated Molecular Weight:27kDa

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Shelf Life:12個月

Storage:儲存於-20°C,有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:27kDa

Dilution:白血球介素 1:200-1:1000;免疫組織化學 1:10-1:50

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Application:免疫組化

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Research Areas:表觀遺傳學和核子訊號

Species Reactivity:人類;大鼠

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Target Synonym:脫氧尿苷 5' 三磷酸核苷酸水解酶;核異構體;脫氧尿苷 5'-三磷酸核苷酸水解酶;粒線體;脫氧尿苷三磷酸酶;dut;DUT;dUTP 核苷酸水解酶;dUTP 焦磷酸酶;dUTPase;FLJ206222222222

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS,PH7.4

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Clonality:多克隆

Conjugation:未結合

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